產(chǎn)品名稱:Interleukin-6 rat ELISA 產(chǎn) 地:Demeditec 產(chǎn)品貨號:DE4845 產(chǎn)品規(guī)格:192 Tests 產(chǎn)品說明: Special remarks: Interleukin-6 (IL-6) is a multi-functional cytokine that regulates immune responses, acute phase reactions and hematopoiesis and may play a central role in host defense mechanisms. IL-6 is usually not produced constitutively by normal cells, but its expression is readily induced by a variety of cytokines, lipopolysaccharide or viral infections. IL-6 is a pleiotropic cytokine produced by a variety of cells. It acts on a wide range of tissues, exerting growth-induction, growth-inhibition, and differentiation respectively, depending on the nature of the target cells. IL-6 is involved in -the induction of B-cell differentiation, -the induction of acute phase proteins in liver cells, -growth promotion of myeloma/plasmacytoma/hybridoma cells, -induction of IL-2 and IL-2 receptor expression, -proliferation and differentiation of T cells, -inhibition of cell growth of certain myeloid leukemic cell lines and induction of their differentiation to macrophages, -enhancement of IL-3-induced multipotential colony cell formation in hematopoietic stem cells and induction of maturation of megakaryocytes as a thrombopoietic factor, -induction of mesangial cell growth, -induction of neural differentiation of PC 12 cells and -induction of keratinocyte growth The abnormal production of IL-6 was first suggested to be related to polyclonal B-cell activation with autoantibody production in patients with cardiac myxoma. Since then, IL-6 has been suggested to be involved in the pathogenesis of a variety of diseases. Measurement of IL-6 levels in serum and other body fluids thus provides more detailed insights into various pathological situations. 上海玉博生物技術(shù)有限公司在為生命科學領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于****地位,公司提供的產(chǎn)品涵蓋了二十多個國家近五十萬種產(chǎn)品,而且產(chǎn)品的數(shù)量與信息在不斷的增長和更新,公司提供的產(chǎn)品能夠使生命科學工作者加快對生物化學,分子生物學,細胞生物學以及蛋白質(zhì)組學研究的認知,以及分子診斷和臨床醫(yī)學領(lǐng)域的應用。
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