SHBG IRMA

產品名稱：SHBG IRMA
產    地：Demeditec 
產品貨號：DE46100
產品規格：100 Tests
產品說明：
Special remarks:
Sex hormone-binding globulin (SHBG), also known as Testosterone-estradiol binding globulin (TEBG) and sex steroid binding protein (SBP), is a circulating glycoprotein with a molecular weight of around 86000. It is thought to be synthesized in the liver, and in the circulation its biological function is the transport of sex steroid hormones.It has a high binding affinity for testosterone, dihydrotestosterone and estradiol. Serum SHBG levels are relatively low at birth, increase to high levels during infancy, then decrease during puberty. The highest physiologic levels of SHBG are observed in pregnant, near-term maternal serum. Abnormal serum SHBG levels have been reported in number of conditions, including obesity and female hyperandrogenism (including polycystic ovary dicease). Serum SHBG levels are inversely related to free, presumably bioactive, testosterone concentracions, a “free testosterone index” based on the ratio of total testosterone to SHBG has been characterized.
In general the measurement of SHBG offers the possibility for calculating the free fraction of vatious steroid hormones based on the measurement of the total concentration in serum. But there is also a method available for the direct measurement of free steroid hormones in saliva. The metabolic activity of any steroid in any case is just represented by the free hormone fraction which represents less than 5% of the total. The non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering a group of different testkits in ELISA format for the measurement of free steroid hormones in saliva (please check in the chapter "saliva testing").
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。

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