產品名稱：DHEA-S RIA
產    地：Demeditec 
產品貨號：DE44100
產品規格：100 Tests
產品說明：
Special remarks:
Dehydroepiandrosterone sulphate (DHEA-SO4) is almost exclusively synthesized by the adrenal cortex, and it is the most abundant steroid hormone in the peripheral circulation. It is the main source of the urinary 17-ketosteroids. The metabolic clearance of DHEA-SO4 is slow, and it is converted mostly to oestrogens. The hormone has a maximum level from puberty until 20-30 years of age, then there is a gradual decrease in the blood DHEA-SO4 concentration mainly in the menopause of women. Although the physiological role of DHEA?SO4 is not well established the serum level of this steroid hormone has an informative pathophysiological value.
1.The serum DHEA-SO4 radioimmunoassay seems to be a reliable tool to assess adrenal androgen function and the glandular overproduction of androgens.
2.High DHEA-SO4 values indicate a virilizing disorder of adrenal origin in women. This includes mainly adrenal neoplasms or early or late onset of congenital adrenal hyperplasia.
3.Monitoring the DHEA-SO4 concentration may be useful to control the adrenal suppressive therapy (dexamethasone).
4.Low DHEA-SO4 levels can be an indicator of hormone-dependent immunological disorders.
5.Low levels of DHEA-SO4 may be related to the development of diseases that increases with age such as cancer and atherosclerosis. In these circumstances a systematically repeated assessment of the blood DHEA-SO4 values is recommended.
There is also a method available for the measurement of free DHEA in saliva. The metabolic activity of any steroid is just represented by the free hormone fraction which represents less than 5% of the total. The non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering such a testkit in ELISA format with the catalogue number  DESLV3012.
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。

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