hGH

產品名稱：hGH ELISA
產    地：Demeditec 
產品貨號：DE3552
產品規格：96 Tests
產品說明：
Special remarks:
hGH is a polypeptide hormone (molecular weight 21,500 Da) produced by the acidophil cells of the anterior pituitary under the control of two main substances from the median eminence : Growth-hormone Releasing Factor (GRF) and an inhibitory agent, somatostatin.  Dopaminergic, adrenergic and serotoninergic neuroendocrine pathways also play an important role in the control of hGH secretion.  Excitatory stimuli of hGH secretion include hypoglycemia, exercise, fasting, meals with a high protein content, deep sleep, stress, glucagon, L Dopa, amino acids, etc.  Inhibitory stimuli include glucose, cortisol, hGH and free fatty acids.  Because of its short plasma half life (±25 minutes) and of the frequent excitatory or inhibitory stimuli, hGH displays frequent and large variations of concentration in serum.
One of the main physiological functions of hGH is to act on the liver and other tissues to produce Somatomedins, which in turn induce growth by direct action on target tissues.  In contrast to hGH, the concentration of somatomedin in serum is kept stable by virtue of being largely bound to circulating plasma proteins.
Growth retardation
hGH hyposecretion is one of the various causes of small stature in children.  Serum hGH measurement with a highly sensitive assay, especially following a provocative stimulus (absence of response), is an important way to establish this diagnosis because this group of patients can be treated by administration of hGH.
Hypopituitarism
Serum hGH measurement is also an index of pituitary function when hypopituitarism (either idiopathic or due to tumour and surgery) is suspected.
Gigantism and acromegaly
Serum hGH measurement, especially following a provocative inhibitory test (absence of response), is an important way to establish the diagnosis of hGH hypersecretion due to acidophilic pituitary tumour.  This results in gigantism in children and acromegaly in *****s.  Both of these disorders may be treated by surgery or radiation.
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。

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