產(chǎn)品名稱：Bortezomib 產(chǎn)品貨號(hào)：Affix AF3037 產(chǎn)品規(guī)格：25 mg Technical Data Chemical Name [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2- [(pyrazinylcarbonyl)amino]propyl]amino]butyl]-boronic acid; Velcade; DPBA Biological Description Bortezomib is a selective and robust 26S proteasome inhibitor, that is a boronic acid dipeptide derivative. Targeted elimination of damaged or unwanted proteins via the ubiquitin-proteasome pathway is fundamental to the control of many essential cell functions, including cell-cycle progression, gene transcription, and apoptosis. Bortezomib has been reported to inhibit necrosis and cell proliferation, and downregulate metastatic gene expression. Molecular Weight 384.24 daltons Molecular Formula C19H25BN4O4 Solubility Soluble in Chloroform, Dimethyl Sulfoxide, Methanol and Ethanol Purity >99% Storage instructions Up to one week at 4°C or six months at -20°C. CAS No. 179324-69-7 References Jones, M.D., et al. 2010. Clin. Cancer Res. 16
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