產(chǎn)品名稱：Mexiletine Hydrochloride 產(chǎn)品貨號(hào)：Affix AF3023 產(chǎn)品規(guī)格：50 mg Technical Data Chemical Name 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride Biological Description Mexiletine hydrochloride is a use dependent sodium channel blocker of sodium channels in skeletal muscle tissue. In addition, mexiletine can plays an important role in protecting neuronal tissue from oxidative damage. The aryloxy moiety of mexiletine hydrochloride is very important to its function as a sodium channel blocker, as any change to this structure reduces the potency of the compound. Molecular Weight 215.7 daltons. Molecular Formula C11H17NO.HCI Solubility Soluble to 100 mM in Water and to 100 mM in DMSO Purity >98% Storage instructions Up to one week at 4°C or six months at -20°C CAS No. 5370-01-4 References Bellis et al (2006) Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents. Br.J.Pharmacol. 149 300.
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