Oligomycin
產(chǎn)品名稱：Oligomycin
產(chǎn)品貨號(hào)：Affix AF3006
產(chǎn)品規(guī)格：1 G
Technical Data
Chemical Name (1S,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R, 16S,18E,20E,22S,25R,27S,28R,29S)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione
Biological Description Oligomycin is a natural antibiotic isolated from Streptomyces diastatochromogenes which inhibits mitochondrial H+-ATP synthase. Oligomycin: a macrolide antibiotic that inhibits membrane bound mitochondrial ATPase. A mixture of A, B, and C isomers.Oligomycin inhibits the H+- ATP-synthase by binding to the Oligomycin sensitivity-conferring protein (OSCP) at the F(o) subunits 6 and 9.
Molecular Weight 789.3 daltons.
Molecular Formula C45H74O11
Solubility Soluble in Ethanol ,Dichloromethane, DMSO and Acetone
Purity >99 %
Storage instructions Store at -20°C
CAS No. 1404-19-9
References Kagawa, Y. and Racker, E. (1966) J. Biol. Chem. 241, 2461.Van Dyke, R.W. 1993. Am. J. Physiol. 265: C901-C917.
