Calyculin A 原裝

產品名稱：Calyculin A
產品貨號：LC  C-3987
產品規格：1 MG
SPECIAL HAZARD:  TUMOR PROMOTER.  Gloves and mask should be worn when using this compound.  Care must be taken to prevent contact through all routes of exposure.
NOTE:  Do not expose to sunlight or fluorescent lights for extended periods.
Storage:  Store at or below -20 ºC in the dark.  Solubility:  Soluble in DMSO and ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 1-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility  Disposal:  A
Very potent inhibitor (Ki = ca. 0.1 nM) with high specificity for the PP-1 and PP-2 classes of protein serine/threonine phosphatase.  Ishihara, H., et al.  "Calyculin A and okadaic acid: inhibitors of protein phosphatase activity."  Biochem. Biophys. Res. Comm. 159:  871-877 (1989).
Potent non-phorbol type tumor promoter.  Suganuma, M., et al.  "Calyculin A, an inhibitor of protein phosphatases, a potent tumor promoter on CD-1 mouse skin."  Cancer Res. 50:  3521-3525 (1990).
Please request Technical Note #19 for additional information.
Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.

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