產(chǎn)品名稱：Human Regulatory T cell Staining Kit (containing Foxp3 PCH101) PCH101 產(chǎn)品貨號(hào)：eBioscience 88-8998-40 產(chǎn)品規(guī)格：Kit Human Regulatory T Cell Staining Kit #2 Also known as: Forkhead Box P3, Scurfin, JM2, Treg, Foxp3 PCH101 APC; CD4 FITC; CD25 PE RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 88-8998 Cat. No. Size 88-8998-40 Kit Description: Regulatory T cells/Tregs (also known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress immune responses thereby maintaining homeostasis and self tolerance. Intense investigation has tried to determine exclusive protein markers for Tregs. This has been complicated by the identification of four regulatory T cells subsets; natural, anergic, Tr1 and CD8+CD28- suppressor T cells. There are still no cell surface molecules that uniquely distinguish functional regulatory cells from conventional T cells. It has been proposed that the “natural” regulatory T cells originally recognized by their constitutive expression of CD4 and CD25 are further defined by expression of the transcription factor Foxp3. Additionally Foxp3 has also been characterized in CD8+CD28- suppressor T cells. The Regulatory T Cell Staining Kit contains all the necessary reagents to stain natural Tregs including monoclonal antibodies against CD4, CD25 and Foxp3. This kit has been optimized for staining normal hPBMCs. Not included: Isotype control for anti-CD4 and anti-CD25 (cocktail of FITC & PE mouse IgG1, cat. 22-2714)
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