產品名稱：c-Jun (Total) InstantOne™ ELISA 產品貨號：eBioscience 85-86161-11 產品規(guī)格：96 tests c-Jun (Total) InstantOne™ ELISA Also known as: JUN, Transcription factor AP-1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 85-86161 Cat. No. Size 85-86161-11 96 tests Description: The InstantOne™ ELISA is specifically engineered for accurate measurement of total human and mouse c-Jun in cell lysates. Detection of rat c-Jun is also expected. The InstantOne™ ELISA kit allows for fast analysis of samples in approximately one hour. All reagents used in a traditional sandwich ELISA are added in solution to a plate followed by a wash step and detection with the TMB colorimetric substrate. Jun is a member of the Activator Protein-1 (AP-1) family of transcription factors. AP-1 proteins can form homodimers (e.g., Jun/Jun) or heterodimers with other family members (e.g., Jun/Fos). AP-1 activity is highly regulated in normal cells by phosphorylation in response to growth factors, cytokines, and various other intra- and extracellular signals. Jun is phosphorylated at Ser63 and Ser73 by JNK, resulting in the ability of Jun/Jun or Jun/Fos dimers to bind DNA and modulate transcription.
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