anti-mouse CD25 Alexa Fluor® 488 eBio7D4 (7D4) **

產品名稱：anti-mouse CD25 Alexa Fluor® 488 eBio7D4 (7D4) 100 ug
產品貨號：eBioscience 53-0252-82
產品規格：100 ug
Anti-Mouse CD25 Alexa Fluor® 488
Also known as: Interleukin-2 Receptor alpha
Clone: eBio7D4 (7D4)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 53-0252
Cat. No. Size
53-0252-80  25 ug 
53-0252-82  100 ug 
Description: The eBio7D4 antibody reacts with mouse CD25, the 55 kDa interleukin-2 receptor a chain (IL-2Ra). CD25 is expressed by early progenitors of the T and B lineage, as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiation and activation/proliferation. The epitopes recognized by eBio3C7, PC61.5 and eBio7D4 are all different allowing for depletion with one antibody (typically PC61.5) followed by subsequent detection with another one. eBio7D4 has been reported to block IL-2 binding but can be overcome by additional IL-2. The monoclonal antibody PC61.5 (cat. 16-0251) is recommended for in vivo studies.

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