anti-human Toll-like receptor 2 (CD282) Alexa Fluor® 647 TL2.1 **

產品名稱：anti-human Toll-like receptor 2 (CD282) Alexa Fluor® 647 TL2.1 100 tests
產品貨號：eBioscience 51-9922-42
產品規格：100 tests
Anti-Human CD282 (TLR2) Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Format: APC, cat. 17-9922)
Also known as: toll-like receptor 2
Clone: TL2.1
RUO: For Research Use Only. Not for use in diagnostic procedures.
Attention: To Be Discontinued. Refer to Replacement Format APC, cat. 17-9922
SKU# 51-9922
Cat. No. Size
51-9922-41  25 tests 
51-9922-42  100 tests 
Description: The TL2.1 monoclonal antibody reacts with human Toll-like receptor 2 (TLR2). To date, at least ten members of the Toll family have been identified in human. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed by peripheral blood monocytes and is responsible for distinguishing different pathogens. TL2.1, a blocking antibody, has been used to study the role of TLR-2 as a pattern recognition receptor in microbial lipoprotein/lipopeptide induced cytokine production from human peripheral blood mononuclear cells. TL2.1 has been reported to immunoprecipitate human TLR2 (~90 kDa) from PBMC and HMEC.

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