anti-human CD16 eFluorTM 450 eBioCB16 (CB16) **

產品名稱：anti-human CD16 eFluorTM 450 eBioCB16 (CB16) 100 tests
產品貨號：eBioscience 48-0161-82
產品規格：100 tests
Anti-Human CD16 eFluor® 450
Also known as: Low Affinity IgG Receptor 3, FCGR3a, FCGR3, IGFR11
Clone: eBioCB16 (CB16)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 48-0168
Cat. No. Size
48-0168-41  25 tests 
48-0168-42  100 tests 
Description: The eBioCB16 monoclonal antibody recognizes CD16 (Fc gammaRIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80 kDa. CD16 is represented by two similar genes, CD16A (Fc gammaRIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fc gammaRIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation.

產品留言

標題

聯系人

聯系電話

內容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!