Anti-Human CD114 (G-CSFR) (clone LMM741) PerCP-eFluor 710,**

產品名稱：Anti-Human CD114 (G-CSFR) (clone LMM741) PerCP-eFluor 710, 100 tests
產品貨號：eBioscience 46-1149-42
產品規格：100 tests
Anti-Human CD114 (G-CSFR) PerCP-eFluor® 710
Also known as: Granulocyte colony-stimulating factor receptor, CSF3R
Clone: LMM741
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 46-1149
Cat. No. Size
46-1149-41  25 tests 
46-1149-42  100 tests 
Description: This LMM741 monoclonal antibody reacts with human CD114, which is also known as granulocyte colony-stimulating factor receptor (G-CSFR). A type I hematopoietin cytokine receptor, CD114 is expressed on granulocytes such as neutrophils, myeloid cells, monocytes, and leukemic cells. This receptor is absent from lymphocytes, erythrocytes, and eosinophils. CD114 can also be detected on non-hematopoietic cells, including neurons, endothelial cells, and cardiomyocytes. Studies demonstrate that expression of CD114 can be downregulated by LPS, TNF, phorbol ester, and G-CSF itself. Binding of G-CSF binding induces homodimerization of the receptor that activates signaling transduction (e.g., the JAK/STAT and Erk1/2 pathways) to mediate cell proliferation, survival, and differentiation.

產品留言

標題

聯系人

聯系電話

內容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!