Recombinant Mouse IL-17A/F 4

產品名稱：Recombinant Mouse IL-17A/F 4 pack
產品貨號：eBioscience 39-8172-65
產品規格：4 Pack
Mouse IL-17AF (heterodimer) Single-Use ELISA RSG Standard Recombinant
Also known as: Interleukin-17A/F, IL17A/F
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 39-8172
Cat. No. Size
39-8172-65  4 pack 
Description: The interleukin 17 (IL-17) family proteins comprise six members (17A through 17F). However, recent studies found that co-expression of IL-17F and IL-17A in HEK293 cells results in the formation of biologically active IL-17F/IL-17A heterodimers, in addition to the IL-17F homodimers and IL-17A homodimers. Activated human CD4+ T cells were found to produce the IL-17A/F heterodimer, along with the corresponding homodimers. IL-17A was most potent, followed by IL-17A/F heterodimer, then IL-17F (100fold lower than IL-17A). Activated human CD4+ T cells in culture were found to secret IL-17F homodimer at 10-fold higher levels than IL-17A homodimer, suggesting that the majority of the IL-17A protein expressed exists in the form of the IL-17A/F heterodimer.

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