Carrier-Free Recombinant Rat IL-17A (Interleukin-17A, CTLA-8) 500 ug **
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產品名稱: Carrier-Free Recombinant Rat IL-17A (Interleukin-17A, CTLA-8) 500 ug **
產品型號: 34-8170-85
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簡單介紹
Carrier-Free Recombinant Rat IL-17A (Interleukin-17A, CTLA-8) 500 ug **
Carrier-Free Recombinant Rat IL-17A (Interleukin-17A, CTLA-8) 500 ug **
的詳細介紹
Carrier-Free Recombinant Rat IL-17A (Interleukin-17A, CTLA-8) 500 ug **
產品名稱：Carrier-Free Recombinant Rat IL-17A (Interleukin-17A, CTLA-8) 500 ug
產品貨號：eBioscience 34-8170-85
產品規格：500 ug
Rat IL-17A Recombinant Protein Carrier-Free
Also known as: Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 34-8170
Cat. No. Size
34-8170-85 500 ug
Description: Interleukin-17A (IL-17A, also known as CTLA-8 and IL-17) is a member of the IL-17 family of proinflammatory cytokines. It is most similar to IL-17F, another member of the family with which it shares 50% sequence homology. Both cytokines exist as homodimers and individual subunits from each protein can also associate into a heterodimer known as IL-17AF.
Expression of IL-17A is most often associated with the Th17 subset of CD4+ T cells, but has also been observed in CD8+ T cells, γδ T cells, and neutrophils. IL-17A is important as a neutrophil activator, and it induces inflammatory cytokine production in epithelial cells, endothelial cells, and fibroblasts through NF-κB signaling. IL-17A and Th17 cells have been implicated in various autoimmune disorders.
