產品名稱：Anti-Mouse CD279 (PD-1) (clone RMP1-30) APC, 100 ug 產品貨號：eBioscience 17-9981-82 產品規(guī)格：100 tests Anti-Mouse CD279 (PD-1) APC Also known as: Pdcd1, Programmed cell death protein 1 Clone: RMP1-30 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-9981 Cat. No. Size 17-9981-80 25 ug 17-9981-82 100 ug Description: The RMP1-30 antibody reacts with mouse PD-1 (programmed death-1), a 55 kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1–30 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants.
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