APC Human IGF-1R (clone 1H7), **
如果您對(duì)該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: APC Human IGF-1R (clone 1H7), **
產(chǎn)品型號(hào): 17-8849-42
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
APC Human IGF-1R (clone 1H7), **
APC Human IGF-1R (clone 1H7), **
的詳細(xì)介紹
APC Human IGF-1R (clone 1H7), **
產(chǎn)品名稱：APC Human IGF-1R (clone 1H7), 100 ug
產(chǎn)品貨號(hào)：eBioscience 17-8849-42
產(chǎn)品規(guī)格：100 ug
Anti-Human CD221 (Insulin-like Growth Factor-1 Receptor) APC
Also known as: IGF-1R, IGFIR
Clone: 1H7
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 17-8849
Cat. No. Size
17-8849-41 25 tests
17-8849-42 100 tests
Description: This 1H7 monoclonal antibody reacts with human insulin-like growth factor-1 receptor (IGF-1R), also known as CD221. This receptor is a cell surface-expressed glycoprotein composed of two extracellular alpha subunits and two transmembrane beta subunits that possess tyrosine kinase activity. Expressed on nearly all cell types, this receptor binds IGF-I and IGF-II, as well as insulin. Ligand binding leads to activation of the PI3K/Akt and MAPK pathways, which mediate cell proliferation and survival. Many tumors and transformed cells display altered IGF-1R expression.
This monoclonal antibody has been reported to block binding of IGF-I and IGF-II to the IGF-1R.
