產品名稱：Anti-Human CD169 (Siglec-1) APC (7-239), 100 tests
產品規格：eBioscience 17-1699-42
產品貨號：100 tests
Anti-Human CD169 (Siglec-1) APC
Also known as: Sialoadhesin
Clone: 7-239
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 17-1699
Cat. No. Size
17-1699-41  25 tests 
17-1699-42  100 tests 
Description: This 7-239 monoclonal antibody reacts with human CD169, also known as Siglec-1 and Sialoadhesin. This type I transmembrane protein is a member of the sialic acid binding Ig-like lectin (Siglec) family. Expressed on macrophages and dendritic cells in peripheral blood, lymph nodes, and spleen in humans, CD169 binds glycoproteins and glycolipids containing N-acetylneuraminyl alpha 2-3-galactose. CD169 expression can also be induced on CD14+ monocytes by interferon-alpha and interferon-gamma to mediate HIV-1 infection. Finally, CD169 has also been shown to be involved in antigen presentation to invariant NK T cells.
This monoclonal antibody has been reported to inhibit erythrocyte binding to CD169-expressing cells.

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