產(chǎn)品名稱：anti-human CD158f, KIR2DL5 APC (Clone: UP-R1) 100 tests 產(chǎn)品規(guī)格：eBioscience 17-1588-42 產(chǎn)品貨號：100 tests Anti-Human CD158f APC Also known as: Kir2dl5a Clone: UP-R1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-1588 Cat. No. Size 17-1588-41 25 tests 17-1588-42 100 tests Description: This UP-R1 monoclonal antibody recognizes human CD158f, also known as KIR2DL5. CD158f is an inhibitory receptor and a member of the KIR (Killer cell Ig-like receptors) family of receptors, which recognizes subsets of HLA alleles. Expression is found mainly on a subset of NK cells with minimal expression also present on a minor subset of T lymphocytes in some individuals. This new member of the family is highly polymorphic and expression is not found on many human donors. Activation of the receptor and tyrosine phosphoryaltion recruits SHP-2 and SHP-1 to the ITIM cytoplasmic domain. The UP-R1 antibody has been shown to inhibit NK cytotoxicity.
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