產品名稱：anti-mouse CD117 APC ACK2 200 ug 產品規(guī)格：eBioscience 17-1171-83 產品貨號：200 ug Anti-Mouse CD117 (c-Kit) APC Also known as: cKit, Steel Factor Receptor, Mast/stem cell growth factor receptor, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit Clone: ACK2 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-1172 Cat. No. Size 17-1172-81 50 ug 17-1172-82 100 ug 17-1172-83 200 ug Description: The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.
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