anti-human CXCR4 (CD184, Fusin) FG Purified 12G5 **
如果您對(duì)該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: anti-human CXCR4 (CD184, Fusin) FG Purified 12G5 **
產(chǎn)品型號(hào): 16-9999-85
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
anti-human CXCR4 (CD184, Fusin) FG Purified 12G5 **
anti-human CXCR4 (CD184, Fusin) FG Purified 12G5 **
的詳細(xì)介紹
anti-human CXCR4 (CD184, Fusin) FG Purified 12G5 **
產(chǎn)品名稱：anti-human CXCR4 (CD184, Fusin) FG Purified 12G5 500 ug
產(chǎn)品貨號(hào)：eBioscience 16-9999-85
產(chǎn)品規(guī)格：500 ug
Anti-Human CD184 (CXCR4) Functional Grade Purified
Also known as: C-X-C chemokine receptor type 4, Fusin, SDF-1 receptor
Clone: 12G5
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-9999
Cat. No. Size
16-9999-81 50 ug
16-9999-85 500 ug
Description: The 12G5 monoclonal antibody reacts with human CXCR4 (CD184), also termed Fusin, LESTR, or HUMSTR. Fusin is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a coreceptor for X4 HIV-1 entry into CD4+ cells. CXCR4 is expressed predominantly on naive T cell subsets of peripheral blood and is rapidly upregulated by PHA and IL-2 stimulation. 12G5 shows partial inhibition of chemotaxis and calcium influx induced by SDF-1 (the natural ligand of CXCR4), blocks CD4-independent HIV-2 infection, and blocks CD4-dependent infection by some T-tropic HIV-1 isolates.
