產品名稱：anti-mouse FR4 FG Purified eBioTH6 500 ug
產品貨號：eBioscience 16-5446-85
產品規格：500 ug
Anti-Mouse FR4 Functional Grade Purified
Also known as: Folate receptor 4, FOLR4 FRdelta, FRd
Clone: eBioTH6
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-5446
Cat. No. Size
16-5446-82  100 ug 
16-5446-85  500 ug 
Description: The monoclonal antibody eBioTh6 recognizes FR4, also known as FR δ and FBP3 (folate binding protein3). FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naïve T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.
Based on co-staining studies, the epitopes recognized by eBioTH6 and eBio12A5 (cat 51-5445) are different thereby allowing functional studies with TH6 to be evaluated with eBio12A5.

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