產(chǎn)品名稱：Functional Grade Mouse Jagged-1 (clone HMJ1-29), 500 ug 產(chǎn)品貨號(hào)：eBioscience 16-3391-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse CD339 (Jagged 1) Functional Grade Purified Also known as: JAG1, Jagged1 Clone: HMJ1-29 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-3391 Cat. No. Size 16-3391-82 100 ug 16-3391-85 500 ug Description: This HMJ1-29 monoclonal antibody reacts with mouse Jagged-1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Jagged-1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-1 is expressed by thymic lymphoid and stromal cells, as well as macrophages and CD8+CD11c+ dendritic cells in the spleen. The HMJ1-29 antibody is reported to crossreact to rat.
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