Mouse NKp46 (clone 29A1),**
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產(chǎn)品名稱(chēng): Mouse NKp46 (clone 29A1),**
產(chǎn)品型號(hào): 16-3351-85
產(chǎn)品展商: 其他品牌
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Mouse NKp46 (clone 29A1),**
Mouse NKp46 (clone 29A1),**
的詳細(xì)介紹
Mouse NKp46 (clone 29A1),**
產(chǎn)品名稱(chēng)：Mouse NKp46 (clone 29A1), 500 ug
產(chǎn)品貨號(hào)：eBioscience 16-3351-85
產(chǎn)品規(guī)格：500 ug
Anti-Mouse CD335 (NKp46) Functional Grade Purified
Also known as: NCR1, Ly-94
Clone: 29A1.4
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-3351
Cat. No. Size
16-3351-81 50 ug
16-3351-85 500 ug
Description: The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335. CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail. Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells (NKp46+, CD3-). Furthermore, unlike many of the NK markers which also stain NKT cells, staining with 29A1.4 is not strain specific. Staining has been shown on C57Bl/6, SJL, CBA/CA and BALB/C strains. NKp46 has been shown to play a role in NK cell-mediated lysis of several tumor cells and pathogen-infected cell lines.
The 29A1.4 monoclonal antibody has been shown to activate NK cells in vitro. The 29A1.4 monoclonal antibody does not deplete NK cells in vivo.
