產(chǎn)品名稱(chēng)：anti-mouse CD40 FG Purified 1C10 1 mg 產(chǎn)品貨號(hào)：eBioscience 16-0401-86 產(chǎn)品規(guī)格：1 mg Anti-Mouse CD40 Functional Grade Purified Also known as: TNFRSF5 Clone: 1C10 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-0401 Cat. No. Size 16-0401-81 50 ug 16-0401-82 100 ug 16-0401-85 500 ug 16-0401-86 1 mg Description: The 1C10 monoclonal antibody reacts with mouse CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.
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