產(chǎn)品名稱：anti-rat CD3 FG Purified eBioG4.18 (G4.18) 500 ug 產(chǎn)品貨號：eBioscience 16-0030-85 產(chǎn)品規(guī)格：500 ug Anti-Rat CD3 Functional Grade Purified Also known as: T3 Clone: eBioG4.18 (G4.18) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-0030 Cat. No. Size 16-0030-85 500 ug Description: The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.
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