產(chǎn)品名稱：anti-mouse ICOS (CD278) PE-Cy5 15F9 50 ug 產(chǎn)品貨號：eBioscience 15-9940-81 產(chǎn)品規(guī)格：50 ug Anti-Mouse CD278 (ICOS) PE-Cy5 (To be Discontinued; alternative clone Cat. No. 15-9942) Clone: 15F9 RUO: For Research Use Only. Not for use in diagnostic procedures. Attention: Alternative clone 7E.17G9 is available. See Cat. No. 15-9942. SKU# 15-9940 Cat. No. Size 15-9940-81 50 ug Description: The 15F9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. IOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells. The 15F9 antibody is reported to have functional activity.
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