產(chǎn)品名稱：anti-mouse PD-1 (CD279) Purified RMP1-30 500 ug 產(chǎn)品貨號：eBioscience 14-9981-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse CD279 (PD-1) Purified Also known as: Pdcd1, Programmed cell death protein 1 Clone: RMP1-30 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-9981 Cat. No. Size 14-9981-82 100 ug 14-9981-81 50 ug 14-9981-85 500 ug Description: The RMP1-30 antibody reacts with mouse PD-1 (programmed death-1), a 55 kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1–30 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants.
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