Purified anti- mouse, human & other species Musashi-1 (Clone: 14H1) **
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產品名稱: Purified anti- mouse, human & other species Musashi-1 (Clone: 14H1) **
產品型號: 14-9896-82
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簡單介紹
Purified anti- mouse, human & other species Musashi-1 (Clone: 14H1) **
Purified anti- mouse, human & other species Musashi-1 (Clone: 14H1) **
的詳細介紹
Purified anti- mouse, human & other species Musashi-1 (Clone: 14H1) **
產品名稱：Purified anti- mouse, human & other species Musashi-1 (Clone: 14H1) 100 ug
產品貨號：eBioscience 14-9896-82
產品規格：100 ug
Anti-Musashi-1 Purified
Also known as: MSI1, RNA-binding protein Musashi homolog 1
Clone: 14H1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-9896
Cat. No. Size
14-9896-80 25 ug
14-9896-82 100 ug
Description: This 14H1 monoclonal antibody recognizes human Musashi-1 (MSI-1), a 39 kDa RNA binding protein. Musashi-1 is expressed in CNS stem and progenitor cells with decreased expression in differentiating cells. Musashi-1 functions as a translational repressor, directly regulating its target proteins, Numb and p21 (CIP1). Musashi-1 has been shown to be expressed in stem cells in a variety of other tissues such as the gut, stomach, mammary gland, and hair follicles. In addition to normal tissue expression, Musashi-1 expression has been identified in cells from several tumor types, mainly pulmonary and adenocarcinoma, as well as large and small cell carcinomas. Recently, expression of Musashi-1 in ischemic lesions following stroke provides evidence for neurogenesis as well as the role of Musashi-1 in regulating apoptosis.
Musashi-1 is highly conserved and the 14H1 antibody also recognizes mouse and rat Musashi-1.
