產(chǎn)品名稱：Anti-Human Hes1 Purified (4H1HES), 100 ug 產(chǎn)品貨號：eBioscience 14-9799-82 產(chǎn)品規(guī)格：100 ug Anti-Human Hes1 Purified Also known as: bHLHb39, Class B basic helix-loop-helix protein 39 Clone: 4H1HES1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-9799 Cat. No. Size 14-9799-80 25 ug 14-9799-82 100 ug Description: This 4H1HES monoclonal antibody reacts with human Hes1, a 30-kDa basic-helix-loop-helix transcriptional repressor. Hes1 is expressed in thymocytes, as well as neural, retinal, liver, and pancreatic tissues. Expression of Hes1 is controlled by Notch signaling, and thus plays an important role in T cell development. This regulation by Notch is also critical for neural stem cell differentiation and neurogenesis. Reports have demonstrated that Hes1 antagonizes transcription of MASH1, a basic-helix-loop-helix factor involved in neuronal determination. Finally, Hes1 has been associated with Notch-induced T cell acute lymphoblastic lymphoma and other cancers.
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