產(chǎn)品名稱：Affinity purified Anti-basic cytokeratin (clone AE3), 100 ug 產(chǎn)品貨號：eBioscience 14-9000-82 產(chǎn)品規(guī)格：100 ug Anti-Basic Cytokeratin Purified Also known as: keratin Clone: AE3 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-9000 Cat. No. Size 14-9000-80 25 ug 14-9000-82 100 ug Description: The monoclonal antibody AE3 recognizes many members of the basic (Type II) cytokeratin family. Cytokeratins are intermediate filament proteins comprising one component of the cytoskeleton. There are two large families of cytokeratins, acidic and basic, but all contain the same basic domains (i.e. an α-helical core with an N- and C-terminal domain). The proteins are expressed in epithelial cells, but are developmentally regulated. Many tumors also express these cytokeratins, and their expression can help identify the origin of a neoplasm. The AE3 monoclonal antibody recognizes the 65 to 67 triplet, 64, 59, 58, 56, and 52kD proteins (also known as cytokeratin 1, 2, 3, 4, 5, 6, 7 and 8) in mouse, human, rat, primate (cynomolgus and rhesus), dog, cat, rabbit and chicken.
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