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產(chǎn)品名稱(chēng):Human IL-20 Recombinant Protein 25 ug
產(chǎn)品貨號(hào):eBioscience 14-8209-80
產(chǎn)品規(guī)格:25 ug
Human IL-20 Recombinant Protein
Also known as: Interleukin-20, IL20
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-8209
Cat. No. Size
14-8209-62 5 ug
14-8209-80 25 ug
Description: IL-20 is a recently-discovered member of the IL-10 cytokine family. It is expressed by monocytes, dendritic cells, and keratinocytes. IL-20 activates STAT3 in target cells by activating either of two heterodimeric receptor complexes. One of these consists of IL-20Rβ and IL-20Rα and can be activated by IL-19 and IL-24 as well as IL-20. The other, a complex of IL-20Rβ and IL-22Rα, is activated only by IL-20 and IL-24. IL-20 induces the production of proinflammatory cytokines such as IL-1β, IL-6, and TNFα in monocytes and has been implicated in inflammatory conditions such as atherosclerosis, rheumatoid arthritis, and psoriasis. IL-20 also induces the proliferation of hematopoetic progenitor cells and keratinocytes