產(chǎn)品名稱：Human IL-17A Recombinant Protein 25 ug 產(chǎn)品貨號：eBioscience 14-8180-80 產(chǎn)品規(guī)格：25 ug Human IL-17A Recombinant Protein Also known as: Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-8180 Cat. No. Size 14-8180-62 5 ug 14-8180-80 25 ug Description: Interleukin-17A (IL-17A, also known as CTLA-8 and IL-17) is a member of the IL-17 family of proinflammatory cytokines. It is most similar to IL-17F, another member of the family with which it shares 50% sequence homology. Both cytokines exist as homodimers and individual subunits from each protein can also associate into a heterodimer known as IL-17AF. Expression of IL-17A is most often associated with the Th17 subset of CD4+ T cells, but has also been observed in CD8+ T cell, γδ T cells, and neutrophils. IL-17A is important as a neutrophil activator, and it induces inflammatory cytokine production in epithelial cells, endothelial cells, and fibroblasts through NF-κB signaling. IL-17A and Th17 cells have been implicated in various autoimmune disorders. This recombinant protein has been expressed in insect cells and is fully glycosylated. In addition, the E. coli expressed Human IL-17A Recombinant Protein (cat. 14-8179) is also available.
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