anti-mouse RORg(t) (ROR gamma, Retinoid-Related Orphan Receptor gamma) Purified
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產品名稱: anti-mouse RORg(t) (ROR gamma, Retinoid-Related Orphan Receptor gamma) Purified
產品型號: 14-6981-82
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簡單介紹
anti-mouse RORg(t) (ROR gamma, Retinoid-Related Orphan Receptor gamma) Purified B2D
anti-mouse RORg(t) (ROR gamma, Retinoid-Related Orphan Receptor gamma) Purified
的詳細介紹
anti-mouse RORg(t) (ROR gamma, Retinoid-Related Orphan Receptor gamma) Purified B2D
產品名稱：anti-mouse RORg(t) (ROR gamma, Retinoid-Related Orphan Receptor gamma) Purified B2D 100 ug
產品貨號：eBioscience 14-6981-82
產品規格：100 ug
Anti-Mouse ROR gamma (t) Purified
Also known as: RORgamma, RORg, RORg(t), Retinoid-Related Orphan Receptor gamma, RORc
Clone: B2D
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-6981
Cat. No. Size
14-6981-80 25 ug
14-6981-82 100 ug
Description: The B2D monoclonal antibody reacts with the mouse RORγ(t) protein. RORγ is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes RORα and RORβ. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. RORγ is expressed in several tissues including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that alternative transcription results in the expression of an isoform, RORγt, which is expressed exclusively in cells of the lymphoid compartment, namely CD4+CD8+ “double-positive” thymoyctes, Th17 cells of the periphery and lymphoid tissue inducer (Lti) cells of lymphoid organs.
The RORγt isoform differs from RORγ by three unique amino acids at the amino terminus. Therefore, the B2D antibody will react with both the RORγ and RORγt isoforms.
