產(chǎn)品名稱：anti-human/mouse/rat IL-21 Receptor Purified Polyclonal 50 ug 產(chǎn)品貨號：eBioscience 14-6469-81 產(chǎn)品規(guī)格：50 ug Anti-IL-21 Receptor Purified Also known as: Interleukin-21 Receptor, IL-21R, CD360 Clone: Polyclonal RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-6469 Cat. No. Size 14-6469-63 10 ug 14-6469-81 50 ug Description: The polyclonal antibody reacts with human, mouse, and rat IL-21 receptor; the antibody was raised against a synthetic peptide (nitdqsgnysqecgs) corresponding to amino acids 97 to 111 of human IL-21R precursor (1). A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21 (1). The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
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