產(chǎn)品名稱:anti-human/mouse/rat TACE/ADAM17 (C-terminus) Purified Polyclonal 50 ug 產(chǎn)品貨號(hào):eBioscience 14-6202-81 產(chǎn)品規(guī)格:50 ug Anti-TACE (ADAM17) Purified Also known as: TNF-a converting enzyme Clone: Polyclonal RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-6202 Cat. No. Size 14-6202-63 10 ug 14-6202-81 50 ug Description: The polyclonal antibody reacts with human, mouse, and rat TACE; the antibody was raised against residues 807-823 of human ADAM17, also known as TACE (TNF-α Converting Enzyme), and recognizes human, mouse and rat ADAM17. ADAM17/TACE is a member of the ADAM (A Disintegrin And Metalloprotease) family of membrane-anchored glycoproteins comprised of several distinct protein modules, including a pro- and metalloprotease domain, disintegrin domain, cysteine-rich region and an EGF repeat. ADAM17 converts TNF-α from its membrane-bound precursor (26 kDa) to generate the secreted mature form (17 kDa). ADAM17 also processes other molecules such as TNF receptor, TGF-α, and CD62L (L-Selectin). ADAM17 is expressed by a variety of human and mouse tissues.
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