產品名稱：anti-human AITR/GITR Purified eBioAITR 25 ug 產品貨號：eBioscience 14-5875-80 產品規(guī)格：25 ug Anti-Human CD357 (AITR/GITR) Purified Also known as: TNFRSF18, GITR, AITR Clone: eBioAITR RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-5875 Cat. No. Size 14-5875-80 25 ug Description: The monoclonal antibody reacts with human AITR, Activation Inducible TNFR family member, an approximately 25 kDa member of the TNFR superfamily. AITR mRNA is detected in lymph node, peripheral blood leukocytes and weakly in spleen. AITR mRNA expression was upregulated within 24 hour on PMA/ionomycin or PHA stimulated PBMC. At the protein level, AITR is expressed by a small population of activated PBMC. AITR associates with TRAF1, TRAF2 and TRAF3 and induces nuclear factor NF-κB activation via TRAF2. Recently TL6 (AITRL) has been reported as the ligand for AITR. Interaction of AITR with AITRL is important for cross-talk between T lymphocytes and endothelial cells.
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