產(chǎn)品名稱：anti-mouse CD144 (VE-Cadherin) Purified eBioBV14 (BV14) 500 ug 產(chǎn)品貨號(hào)：eBioscience 14-1442-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse CD144 (VE-Cadherin) Purified Also known as: Cadherin5, VE-Cadherin, Cdh5 Clone: eBioBV14 (BV14) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-1442 Cat. No. Size 14-1442-81 50 ug 14-1442-82 100 ug 14-1442-85 500 ug Description: The BV14 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM)+ have the potential to give rise to hematopoietic cells. Cross-blocking experiments suggest that BV14 recognizes a different epitope than another mouse VE-Cadherin monoclonal antibody, BV13.
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