產(chǎn)品名稱：anti-mouse CD137 Purified 17B5 500 ug 產(chǎn)品貨號(hào)：eBioscience 14-1371-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse CD137 (4-1BB) Purified Also known as: Ly-63, TNFRSF9, ILA Clone: 17B5 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-1371 Cat. No. Size 14-1371-81 50 ug 14-1371-82 100 ug 14-1371-85 500 ug Description: The 17B5 monoclonal antibody reacts with mouse CD137, also known as 4-1BB, a member of the TNFR superfamily. CD137 is expressed as monomers, dimers, and tetramers on the surface of activated T cells around day 4-6 after activation through the TCR complex. Interaction of CD137 with its ligand, 4-1BBL, is reported to deliver a costimulatory signal important in the T-APC interaction. Recent data suggests CD317 is expressed on Tregs and may play a role in their proliferation. The monoclonal antibody 17B5 has strong antagonistic effect in in vitro functional assays.
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