產(chǎn)品名稱：anti-human CD40 Purified 5C3 100 ug 產(chǎn)品貨號(hào)：eBioscience 14-0409-82 產(chǎn)品規(guī)格：100 ug Anti-Human CD40 Purified Also known as: TNFRSF5 Clone: 5C3 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-0409 Cat. No. Size 14-0409-80 25 ug 14-0409-82 100 ug Description: The 5C3 monoclonal antibody reacts with human CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. 5C3 is reported to be used for activation of B cells in in vitro functional assays.
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