產(chǎn)品名稱：anti-mouse CD21/CD35 (CR2/CR1) Purified eBio8D9 (8D9) 500 ug 產(chǎn)品貨號(hào)：eBioscience 14-0211-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse CD21/CD35 Purified Also known as: CR2/CR1, C3DR Clone: eBio8D9 (8D9) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-0211 Cat. No. Size 14-0211-81 50 ug 14-0211-82 100 ug 14-0211-85 500 ug Description: The monoclonal antibody eBio8D9 reacts with an eptiope shared by mouse CD21 (CR2) and CD35 (CR1). CD21 and CD35 are alternatively spliced transcripts from the Cr2 gene, which produce cell-surface proteins of 145 and 190 kDa, respectively. CD21 and CD35 are expressed by mature B cells, but not on thymocytes, peripheral T cells, erythrocytes or platelets. Furthermore, there is some evidence which demonstrates their expression on macrophages. CD21 is a receptor for the complement component C3d and Epstein-Barr virus (EBV). In association with CD19 and CD81, CD21 also participates in B-cell activation through the B cell receptor. Cr2-deficient mice display impaired inflammatory and humoral immune responses in vivo. The anti-mouse CD21/35 monoclonal antibody clones eBio4E3 and eBio8D9 do not cross-block each other, suggesting that they bind to different epitopes.
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