產(chǎn)品名稱：anti-mouse CD8a Purified 53-6.7 1 mg 產(chǎn)品貨號：eBioscience 14-0081-86 產(chǎn)品規(guī)格：1 mg Anti-Mouse CD8a Purified Also known as: CD8 alpha, Ly-2, Ly-35, Ly-B, Lyt-2 Clone: 53-6.7 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-0081 Cat. No. Size 14-0081-82 100 ug 14-0081-85 500 ug 14-0081-86 1 mg Description: The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.
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