產(chǎn)品名稱：anti-mouse MD-1 Biotin MD14 100 ug 產(chǎn)品貨號(hào)：eBioscience 13-9921-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse MD-1 Biotin Also known as: MD1 Clone: MD14 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 13-9921 Cat. No. Size 13-9921-82 100 ug 13-9921-81 50 ug Description: The MD14 monoclonal antibody reacts with mouse MD-1, a 28 kDa molecule, which physically associates with the extracellular portion of RP105 (CD180). MD-1 is expressed by mature B cells, monocytes/macrophages and dendritic cells. The coexpression of MD-1 is indispensable for cell surface expression of RP105 and LPS recognition and signaling. Several monoclonal antibodies to mouse MD-1, including MD14 and MD113, have been reported to be antagonistic for LPS-induced B cell proliferation and CD86 upregulation, while the anti-mouse CD180 (clone RP/14, Cat. No. 16-1801) is reported to exert potent mitogenic effect. The mAb MD113 (Cat. No. 16-9931) is reported to suppress LPS-induced B cell responses to a higher degree than MD14.
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