產品名稱：Biotin anti-mouse Granzyme B 50 ug
產品貨號：eBioscience 13-8821-81
產品規格：50 ug
Anti-Mouse Granzyme B Biotin
Also known as: GrzB, GrB
Clone: eBioLUEE
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-8821
Cat. No. Size
13-8821-81  50 ug 
Description: The eBioLUEE antibody reacts with mouse Granzyme B (GrB) which is a member of the granzyme serine protease family. GrB is found in the granules of cytotoxic T cells and NK cells. Granzyme B has also been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation. GrB has been called CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. GrB is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved has been identified as mannose 6-phosphate receptor. This receptor functions as a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.
 

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