產(chǎn)品名稱：anti-human HVEM (herpes virus entry mediator) Biotin eBioHVEM-122 25 ug 產(chǎn)品貨號：eBioscience 13-5969-80 產(chǎn)品規(guī)格：25 ug Anti-Human CD270 (HVEM) Biotin Also known as: TNFRSF14, HVEM Clone: eBioHVEM-122 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 13-5969 Cat. No. Size 13-5969-80 25 ug Description: The eBioHVEM-122 antibody reacts with Herpes Virus Entry Mediator (HVEM, TR2), a member of the TNF-receptor superfamily. HVEM is found on most cell types, including T cells, B cells, monocytes, neutrophils and dendritic cells. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of HVEM was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. Recent studies have shown HVEM as a unique ligand for BTLA (B and T lymphocyte attenuator). The conservation of the BTLA-HVEM interaction between mouse and human suggests that this system is an important pathway regulating lymphocyte activation and/or homeostasis in the immune response.
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