產(chǎn)品名稱:anti-mouse GITR Biotin DTA-1 25 ug 產(chǎn)品貨號(hào):eBioscience 13-5874-80 產(chǎn)品規(guī)格:25 ug Anti-Mouse CD357 (GITR) Biotin Also known as: TNFRSF18, AITR Clone: DTA-1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 13-5874 Cat. No. Size 13-5874-80 25 ug 13-5874-82 100 ug Description: The DTA-1 monoclonal antibody reacts with mouse GITR, Glucocorticoid-Induced TNFR family gene, also known as TNFRSF18. In naïve mice, GITR is expressed predominantly by CD4+CD25+ T regulatory cells (Treg) and by CD25+ CD4+ CD8- thymocytes. Stimulation of GITR abrogates Treg cell-mediated suppression. The removal of GITR-expressing Treg cells or the administration of DTA-1 resulted in organ specific autoimmune disease.
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