產品名稱：anti-mouse TIM-1 Biotin RMT1-10 50 ug
產品貨號：eBioscience 13-5862-81
產品規格：50 ug
Anti-Mouse TIM1 Biotin (To be Discontinued; refer to 13-5861)
Also known as: TIM-1, HAVCR1, T cell immunoglobulin domain, mucin-like domain
Clone: RMT1-10
RUO: For Research Use Only. Not for use in diagnostic procedures.
Attention: To be disocntinued. Alternative clone is available as 13-5861.
SKU# 13-5862
Cat. No. Size
13-5862-81  50 ug 
13-5862-82  100 ug 
13-5862-85  500 ug 
Description: The RMT1-10 monoclonal antibody reacts with mouse TIM-1, a member of newly identified T cell immunoglobulin domain, mucin-like domain (TIM) gene family. RMT1-10 reacts with TIM-1 from C57Bl/6 mouse. RMT1-4, another antibody specific for TIM-1, reacts with the TIM-1 protein from both BALB/c and C57Bl/6 strains. TIM family of proteins are transmembrane proteins expressed by CD4 T cells. Recent studies demonstrate that the TIM family, particularly TIM-1, plays a critical role in immune responses that regulate the development of atopic diseases. Human TIM-1 is a functional receptor for hepatitis A virus (HAV). In humans, certain polymorphic variants of TIM-1 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV). Activation of T cells through TIM-1 by HAV or by its natural ligand may affect T cell differentiation and the development of Th2-driven allergic inflammatory responses.
 

產品留言

標題

聯系人

聯系電話

內容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!