eBioscience 13-3392-82 Mouse Jagged-2 (clone HMJ2-1), 100 ug
如果您對(duì)該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: eBioscience 13-3392-82 Mouse Jagged-2 (clone HMJ2-1), 100 ug
產(chǎn)品型號(hào): 13-3392-82
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
eBioscience 13-3392-82 Mouse Jagged-2 (clone HMJ2-1), 100 ug
eBioscience 13-3392-82 Mouse Jagged-2 (clone HMJ2-1), 100 ug
的詳細(xì)介紹
eBioscience 13-3392-82 Mouse Jagged-2 (clone HMJ2-1), 100 ug
產(chǎn)品名稱：Mouse Jagged-2 (clone HMJ2-1), 100 ug
產(chǎn)品貨號(hào)：eBioscience 13-3392-82
產(chǎn)品規(guī)格：100 ug
Anti-Mouse Jagged 2 Biotin
Also known as: JAG2
Clone: HMJ2-1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-3392
Cat. No. Size
13-3392-80 25 ug
13-3392-82 100 ug
Description: This HMJ2-1 monoclonal antibody reacts with mouse Jagged-2, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g., Notch 1-4), Jagged-2 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-2 is expressed by thymic lymphoid and stromal cells, as well as macrophages and dendritic cells in the spleen.
Note: Staining of endogenous splenic dendritic (CD8+CD11c+) cells could only be consistently confirmed in cells isolated from C57BL/6, but not Balb/c, mice. Other strains have not been tested. The antiobdy has been reported to crossreact to rat and have blocking function.
