產品名稱：anti-mouse CD201 (EPCR) Biotin eBio1560 (1560) 100 ug 產品貨號：eBioscience 13-2012-82 產品規(guī)格：100 ug Anti-Mouse CD201 (EPCR) Biotin Also known as: Endothelial Protein C Receptor Clone: eBio1560 (1560) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 13-2012 Cat. No. Size 13-2012-80 25 ug 13-2012-82 100 ug Description: The eBio1560 monoclonal antibody reacts with mouse Endothelial Protein C Receptor (EPCR, CD201), a 25 kDa Type 1 transmembrane protein expressed on endothelial cells. EPCR exhibits sequence and structural homology with the MHC class I/CD1 family of proteins. EPCR is a ligand for Protein C and plays an important role in augmenting Protein C activation by the thrombin-thrombomodulin complex and in regulating blood coagulation and inflammation. Deletion of EPCR results in embryonic lethality, at least partically due to placental thrombosis. Recently, it was demonstrated that EPCR expression identified cells in the bone marrow that are capable of hematopoietic reconstitution activity comparable to hematopoietic stem cells isolated with conventional methods. The eBio1560 monoclonal antibody can be used for the detection of these hematopoietic stem cells, however the eBiomRCR-16 monoclonal antibody should only be used for the detection of CD201 on endothelial cells.
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